Abstract Background CHD5 is a conventional tumour-suppressing gene in many tumours.The aim of this study was to determine whether CHD5 variants contribute to the risk of hepatocellular carcinoma (HCC).Methods Gene variants were identified using next-generation sequencing targeted on referenced mutations followed by TaqMan genotyping in two case-con
Considering that the precise delivery of Celastrol (Cst) into mitochondria to induce mitochondrial dysfunction may be a potential approach to improve the therapeutic outcomes of Cst on TNBC, a novel tumor mitochondria dual-targeted mixed-micelle nano-system was fabricated via self-synthesized triphenylphosphonium-modified cholesterol (TPP-Chol) and
In Brazil, most studies of the Culicidae family are concentrated in rainforest regions.As such, there is a lack of knowledge Leather Tote Bag regarding the diversity of Culicidae in regions with different climatic and vegetational characteristics.The aim of this study was to compile an inventory of Culicidae in protected areas of the semi-arid regi